Researchers acknowledged that lifestyle changes may have also contributed, but nevertheless speculated that the drug may reduce oxidative stress and subsequent VEGF overexpression.
Mesopic dysfunction was found following previous predominant rod-mediated function loss, whereas the overall highest functional loss was detected with development of cRORA lesions.
Following cataract surgery, the pathology developed in 23% of eyes with filtering lens implants and 19% without. Mean annual increases, however, were 0.78mm2 and 1.26mm2, respectively.
The most significant inner retinal alterations were observed in those with late-stage disease and/or GA, while little difference was noted between early and intermediate macular degeneration.